guojilianmengdebaogao：hengwenjirouliudejiyinzufenleihelinchuangjieguo
关键词：hengwenjirouliu；jiyinzufenlei
目的：hengwenjirouliushiertongshiqizuichangjianderuanzuzhirouliu。jinguanjinxinglejijidezhiliao，danzhuanyixinghuofufaxingjibinghuanzhede 5 nianshengcunlvrengranhendi，bingqiechule pax-foxo1 ronghezhuangtai，wukeyongyufengxianfencengdejiyinzubiaoji。womentichuleyixiangguojilianmengyanjiu，zhizaiquedingqudongtubiandefashenglvjiqiyulinchuangjieguodeguanlian。
患者和方法：congcanjiaertongzhongliuxuezushiyan（1998-2017）hecanjiaexingjianchongzhizhongliuhe rms2005（1995-2016）shiyandeyingguohuanzheshoujidezhongliuyangbenjinxingdingzhibuhuocexu。quedingletubian、charuqueshi、jiyinqueshihekuozeng，bingjinxingleshengcunfenxi。
结果：laizi 641 minghuanzhede dna shihejinxingfenxi。meigezhongliufaxianyigetubiandezhongweishu。zai foxo1 rongheyinxingdebinglizhong，renyi ras tongluchengyuandetubianfashengzai > 50% debinglizhong，21% debingliweifaxianjiadingdequdongtubian。bcor （15%）、nf1 （15%） he tp53 （13%） tubiandefashenglvgaoyuxianqianbaogao，bingqie tp53 tubianyurongheyinxinghe foxo1 rongheyangxingbinglidejiaochajieguoxiangguan。ras yaxingdetubianzhuyaofashengzai
结论：zheishiqijinweizhilinchuangzhushihengwenjirouliuzhongliudezuidajiyinzutezheng，tigonglegaishanfengxianfencengdeyuhouyichuantezheng，bingjiangnaruqianzhanxingshiyan。
本文仅供医疗卫生等专业人士参考
cehua：goeun，meizhe
titulaiyuan：zhankuhailuoplus
shern jf, selfe j, izquierdo e, et al. genomic classification and clinical outcome in rhabdomyosarcoma: a report from an international consortium. j clin oncol. 2021 jun 24; jco2003060. doi: 10.1200/jco.20.03060.
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